Common side effects
- Nausea or an upset stomach
- Tiredness
- Headache
- Loose stools
- Trouble sleeping or vivid dreams
These are usually mild and short-lived. Taking the dose with food, at the same time each day, often helps. Your physician can suggest simple remedies and, if needed, prescribe something for nausea.
Rare but important
Call your physician straight away if you notice yellowing of the skin or eyes, a spreading rash, severe abdominal pain, or feel very unwell. These are uncommon, but they need prompt review.
Do not stop early
PEP works best when you take the full 28 days without missing doses. If you miss one, take it as soon as you remember and tell your physician. If side effects are making it hard, speak to your physician before stopping. There is almost always a way to make it easier, including switching one of the medicines.
How we support you
Every Hollis course is managed by one physician, with check-ins during the 28 days. PEP Complete adds a side-effect comfort kit, weekly check-ins and a direct WhatsApp line to your physician.
This guide is general information, not a diagnosis. Every situation is different, so speak to a physician about yours. If you are in immediate danger, call 999.
