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How soon do you need PEP?

As soon as possible, and no later than 72 hours after the exposure. Every hour counts, which is why Hollis has a physician on duty 24/7 who can be at your door within about 2 hours.

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  • IdealWithin hours
  • Latest72 h
  • Course28 days
A Hollis nurse in green scrubs holding a tablet and a pharmacy bag

Why earlier is better

After an exposure, HIV takes some time to establish itself in the body. PEP works by stopping the virus during this window. The earlier the first dose, the better the chance it works. After 72 hours, PEP is no longer recommended because the chance of benefit is too low.

If it has been more than 72 hours

PEP is not recommended, but that does not mean there is nothing to do. The physician can arrange the right tests at the right time, and advise you about PrEP if you are likely to be at risk again.

Does the medicine change with time?

No. The recommended PEP regimen is the same whether you start at hour 2 or hour 70: a combination of three HIV medicines taken for 28 days. Your physician may choose a different combination based on your health, other medicines, or what is known about the other person's treatment.

This guide is general information, not a diagnosis. Every situation is different, so speak to a physician about yours. If you are in immediate danger, call 999.

Questions

Common questions.

Still unsure? The physician on duty can talk it through with you, any hour.

Is 48 hours too late for PEP?

No. PEP can be started up to 72 hours after the exposure. Call now so it can start as soon as possible.

Can I take PEP the next day after work?

Please do not wait. Every hour counts, and a physician can come to you at any hour, including late at night.

What if I miss a dose?

Take it as soon as you remember, unless it is almost time for the next one. Your physician will explain exactly what to do for your regimen.

Related guides.

PEPPEP in Dubai, started at your door.Read PEPThink you were exposed to HIV? Here is what to do now.Read PEPPEP side effects, and how to handle them.Read PreventionPrEP, started and managed from home.Read